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งานวิจัยที่สนใจ : Systems Biology, Biomimetic Peptides, Bioactive Peptides, Bioinformatics

ฺOur Bioinformatic Tools (Webserver) for Bioactive Peptide Prediction:

1. TIPred: a novel stacked ensemble approach for the accelerated discovery of tyrosinase inhibitory peptides 
2. TROLLOPE: A novel sequence-based stacked approach for the accelerated discovery of linear T-cell epitopes of hepatitis C virus 
3. PSRQSP: An effective approach for the interpretable prediction of quorum sensing peptide using propensity score representation learning
4. iAMAP-SCM: a novel computational tool for large-scale identification of antimalarial peptides using estimated propensity scores of dipeptides 

5. SCMB3PP: Improved prediction and characterization of blood-brain barrier penetrating peptides using estimated propensity scores of dipeptides 

6. MetaNaBP: Leveraging a meta-learning approach to advance the accuracy of Nav blocking peptides prediction 
7. StackPAP: Accelerating the discovery of plant allergenic proteins using a stacked ensemble-learning framework 

ผลงานแต่งหรือเรียบเรียง ตำรา หนังสือหรือบทความทางวิชาการ:  

1. Yeast expression systems for industrial biotechnology. Gene Expression Systems in Fungi: Advancements and Applications. 227-237. Springer International Publishing.

2. Informatics for Metabolomics. Translational Biomedical Informatics, 91-115. Springer Singapore.

งานวิจัย / ผลงานตีพิมพ์เผยแพร่ :                                                                     

• Charoenkwan, P., Kongsompong, S., Schaduangrat, N., Chumnanpuen, P., & Shoombuatong, W. (2023). TIPred: a novel stacked ensemble approach for the accelerated discovery of tyrosinase inhibitory peptides. BMC bioinformatics, 24(1), 356.
• Charoenkwan, P., Waramit, S., Chumnanpuen, P., Schaduangrat, N., & Shoombuatong, W. (2023). TROLLOPE: A novel sequence-based stacked approach for the accelerated discovery of linear T-cell epitopes of hepatitis C virus. Plos one, 18(8), e0290538.
• Nualnisachol, P., Chumnanpuen, P., & E-kobon, T. (2023). Understanding Snail Mucus Biosynthesis and Shell Biomineralisation through Genomic Data Mining of the Reconstructed Carbohydrate and Glycan Metabolic Pathways of the Giant African Snail (Achatina fulica). Biology, 12(6), 836.
• Charoenkwan, P., Chumnanpuen, P., Schaduangrat, N., Oh, C., Manavalan, B., & Shoombuatong, W. (2023). PSRQSP: An effective approach for the interpretable prediction of quorum sensing peptide using propensity score representation learning. Computers in Biology and Medicine, 158, 106784.
• Kongsompong, S., E-kobon, T., Taengphan, W., Sangkhawasi, M., Khongkow, M., & Chumnanpuen, P. (2023). Computer-Aided Virtual Screening and In Vitro Validation of Biomimetic Tyrosinase Inhibitory Peptides from Abalone Peptidome. International Journal of Molecular Sciences, 24(4), 3154.
• Prasertsuk, K., Prongfa, K., Suttiwanich, P., Harnkit, N., Sangkhawasi, M., Promta, P., & Chumnanpuen, P. (2022). Computer-Aided Screening for Potential Coronavirus 3-Chymotrypsin-like Protease (3CLpro) Inhibitory Peptides from Putative Hemp Seed Trypsinized Peptidome. Molecules, 28(1), 50.
• Hanchanachai, N., Chumnanpuen, P., E-kobon, T. (2022). Effect of conditioned media from Aeromonas caviae on the transcriptomic changes of the porcine isolates of Pasteurella multocida. BMC Microbiology 22 (1), 1-12.
• Charoenkwan, P., Schaduangrat, N., Lio, P., Moni, M.A., Chumnanpuen, P., Shoombuatong, W. (2022). iAMAP-SCM: A Novel Computational Tool for Large-Scale Identification of Antimalarial Peptides Using Estimated Propensity Scores of Dipeptides. ACS Omega, DOI: 10.1021/acsomega.2c04465.
• Charoenkwan, P., Chumnanpuen, P., Schaduangrat, N., Lio, P., Moni, M.A., Shoombuatong, W. (2022). Improved prediction and characterization of blood-brain barrier penetrating peptides using estimated propensity scores of dipeptides. Journal of Computer-Aided Molecular Design, 1-16.
• Harnkit, N., Khongsonthi, T., Masuwan, N., Prasartkul, P., Noikaew, T., Chumnanpuen, P. (2022). Virtual Screening for SARS-CoV-2 Main Protease Inhibitory Peptides from the Putative Hydrolyzed Peptidome of Rice Bran. Antibiotics 11 (10), 1-15.
• Cheawchanlertfa, P., Chitcharoen, S., Raethong, N., Liu, Q., Chumnanpuen, P., Soommat, P., Song, Y., Koffas, M., Laoteng, K., Vongsangnak, W. (2022). Enhancing Genome-Scale Model by Integrative Exometabolome and Transcriptome: Unveiling Carbon Assimilation towards Sphingolipid Biosynthetic Capability of Cordyceps militaris. Journal of Fungi 8 (8), 887.
• Srichairat, N., Taksintum, W., Chumnanpuen, P. (2022). Histological and histochemical characteristics of the oral, pharyngeal and accessory digestive organs in the water monitor lizard (Varanus salvator) from Thailand. Anatomia Histologia Embryologia 52, 1-9.
• Wattayagorn, V., Kongsema, M., Tadakittisarn, S., Chumnanpuen, P. (2022) Riceberry Rice Bran Protein Hydrolyzed Fractions Induced Apoptosis, Senescence and G1/S Cell Cycle Arrest in Human Colon Cancer Cell Lines. Applied Sciences 12 (14), 6917.
• Srichairat, N., Taksintum, W., Chumnanpuen, P. (2022). Histological and histochemical studies of the gastrointestinal tract in the water monitor lizard (Varanus salvator). Acta Zoologica 103 (3), 376-387.
• Fungfuang, W., Pitiporntapin, S., Chumnanpuen, P. Srakaew, N., Chotimanukul, S., Kovitvadhi, U. (2022). Developing of Bachelor Student’s Learning Achievement in Basic Research Methods in Science through Constructivist-based teaching. International Journal of Science Educators and Teachers 1(1), 32-43.
• Chalongkulasak, S., E-kobon, T., Chumnanpuen, P. (2022). Prediction of Antibacterial Peptides against Propionibacterium acnes from the Peptidomes of Achatina fulica Mucus Fractions. Molecules 27 (7), 2290.
• Jansong, C., Pitiporntapin, S., Chumnanpuen, P., Hines, LM., Yokyong, S. (2022). Using socio-scientific issues-based teaching to develop grade 10 students’ informal reasoning skills. Kasetsart Journal of Social Sciences 43 (1), 217–222.
• Chantawannakul, J., Chatpattanasiri, P., Wattayagorn, V., Kongsema, M., Noikaew, T., Chumnanpuen, P. (2021). Virtual Screening for Biomimetic Anti-Cancer Peptides from Cordyceps militaris Putative Pepsinized Peptidome and Validation on Colon Cancer Cell Line. Molecules 26 (19), 5767.
• Pasomboon, P., Chumnanpuen, P., E-kobon, T. (2021). Modified Genome-Scale Metabolic Model of Escherichia coli by Adding Hyaluronic Acid Biosynthesis-Related Enzymes (GLMU2 and HYAD) from Pasteurella multocida. International Journal of Biotechnology and Bioengineering 15 (5), 54-58.
• Pasomboon, P., Chumnanpuen, P., E-kobon, T. (2021). Comparison of Hyaluronic Acid Biosynthetic Genes From Different Strains of Pasteurella multocida. Bioinformatics and Biology Insights 15, 11779322211027406.
• Tachapuripunya, V., Roytrakul, S., Chumnanpuen, P. Teerasak E-kobon. (2021). Unveiling Putative Functions of Mucus Proteins and Their Tryptic Peptides in Seven Gastropod Species Using Comparative Proteomics and Machine Learning-Based Bioinformatics Predictions. Molecules 26 (11), 3475.
• Kongsompong, S., E-kobon, T., Chumnanpuen, P. (2021) K-Nearest Neighbor and Random Forest-Based Prediction of Putative Tyrosinase Inhibitory Peptides of Abalone Haliotis diversicolor. Molecules 26 (12), 3671.
• Hanchanachai, N., Chumnanpuen, P., E-kobon, T. (2021). Interaction study of Pasteurella multocida with culturable aerobic bacteria isolated from porcine respiratory tracts using coculture in conditioned media. BMC microbiology 21 (1), 1-13.
• Nguyen, T. V., Chumnanpuen, P., Parunyakul, K., Srisuksai, K., Fungfuang, W. (2021). A study of the aphrodisiac properties of Cordyceps militaris in streptozotocin-induced diabetic male rats. Veterinary World 14 (2), 537.
• Azam, F. M., Zamri-Saad, M.,  Rahim, R. A.,  Chumnanpuen, P.,  E-Kobon, T.,  Othman, S. (2021). Molecular characterisation of the gdha- derivative of Pasteurella multocida b:2. Pertanika Journal of Tropical Agricultural Science 44 (1), 171-192.
• Nguantad, S., Chumnanpuen, P., Thancharoen, A., Vongsangnak, W., Sriboonlert, A. (2020). Identification of potential candidate genes involved in the sex determination cascade in an aquatic firefly, Sclerotia aquatilis (Coleoptera, Lampyridae).  Genomics 112 (3): 2590-2602.
• Kantawong, F., Jearasakwattana, T., Nira, A., Chewae, J., Sajjamongkol, P., Phothong, P., Chumnanpuen, P. (2020). PI3K/Akt signaling involved with osteoinductive effects of Achatina fulica mucus. Brazilian Archives of Biology and Technology 63: e20180501.
• Wongsa, B., Raethong, N., Chumnanpuen, P., Wong-ekkabut, J., Laoteng, K., Vongsangnak, W. (2020). Alternative metabolic routes in channeling xylose to cordycepin production of Cordyceps militaris identified by comparative transcriptome analysis. Genomics 112 (1): 629-636.
• Suwannapan, W., Ngankoh, S., E-kobon, T., Chumnanpuen, P. (2019). Mucous cell distribution and mucus production during early growth periods of the giant African snail (Achatina fulica). Agriculture and Natural Resources 53 (4): 423-428.
• Jatuponwiphat, T., P. Chumnanpuen, S. Othman, T. E-kobon and W. Vongsangnak (2019). Iron-associated protein interaction networks reveal the key functional modules related to survival and virulence of Pasteurella multocida. Microbial Pathogenesis 127: 257-266.
• Tongmai, T., Maketon, M., Chumnanpuen, P. (2018). Prevention potential of Cordyceps militaris aqueous extract against cyclophosphamind-induced mutagenicity and sperm abnormality in rats. Agriculture and Natural Resources 52(5), 419-423.
• Suwannapan, W., Chumnanpuen, P., & E-kobon, T. (2018). Amplification and bioinformatics analysis of conserved FAD-binding region of L-amino acid oxidase (LAAO) genes in gastropods compared to other organisms. Computational and Structural Biotechnology Journal 16, 98-107.
• Srichairat, N., W. Taksintum, P. Chumnanpuen. (2018). Gross Anatomy of Digestive Organs in Water Monitor Lizard Varanus salvator (Squamata: Varanidae). Walailak Journal of Science and Technology 15 (3).
• Muikham, I., N. Srakaew, K. Chatchavalvanich, P. Chumnanpuen.  (2017). Microanatomy of the digestive system of Supachai's caecilian, Ichthyophis supachaii Taylor, 1960 (Amphibia: Gymnophiona). Acta Zoologica 98 (3), 252-270
• Vongsangnak, W., P. Chumnanpuen, A. Sriboonlert. (2016). Transcriptome analysisreveals candidate genes involved in luciferin metabolism in Luciola aquatilis (Coleoptera: Lampyridae). PeerJ. (2016) e2534. 
• E-kobon, T., K.; Thongararm, P.; Roytrakul, S.; Meesuk, L.; Chumnanpuen, P. (2016). Prediction of anticancer peptides against MCF-7   breast cancer cells from the peptidomes of Achatina fulica mucus fractions. Computational and structural biotechnology journal. 14, 49-57. 
• Kantawong, F., P. Thaweenan, S. Mungkala, S. Tamang, R. Manaphan, P. Wanachantararak, T. E-kobon, P. Chumnanpuen. (2015). Mucus of Achatina fulica stimulates mineralization and inflammatory response in dental pulp cells. Turkish Journal of Biology 3: 1-7.
• Pewhom, A., P. Chumnanpuen, I. Muikham, K. Chatchavalvanich and N. Srakaew. (2014). Histomorphological studies of the testis and male genital ducts of Supachai's caecilian, Ichthyophis supachaii Taylor, 1960 (Amphibia: Gymnophiona). Acta Zoologica 97 (1), 76-89.
• Chumnanpuen, P., M.A.E. Hansen, J. Smedsgaard, J. Nielsen. (2014). Dynamic metabolic footprinting reveals the key components of metabolic network in yeast Saccharomyces cerevisiae.  International journal of genomics 2014, 894296.
• Chumnanpuen, P., I. Nookaew, J. Nielsen. (2013). Integrated analysis, transcriptome-lipidome, reveals the effects of INO-level (INO2 and INO4) on lipid metabolism in yeast.  BMC systems biology 7 (3), 1-14
• Khoomrung, S, P. Chumnanpuen, S. Jansa-Ard, M. Ståhlman, I. Nookaew, J. Borén and J. Nielsen. (2013). Rapid Quantification of Yeast Lipid using Microwave-Assisted Total Lipid Extraction and HPLC-CAD. Analytical Chemistry 85(10): 4912-4919.
• Chumnanpuen, P., J. Zhang, I. Nookaew, J. Nielsen. (2012). Integrated analysis of the transcriptome-lipidome reveals the co-influences of inositol-choline and Snf1 in controlling lipid biosynthesis in yeast. Mol Genet Genomics. 287(7): 541-54.
• Khoomrung, S., S. Jansa-ard, I. Nookaew, J. Nielsen. (2012). Fast and accurate preparation fatty acid methyl esters by microwave-assisted derivatization in yeast Saccharomyces cerevisiae. Applied Microbiology and Biotechnology 94 (6), 1637-1646.
• Chumnanpuen P., Brackmann C., Nandy .K.,Chatzipapadopoulos S., Nielsen J., Enejder. A. (2011).  Lipid biosynthesis monitored at the single-cell level in Saccharomyces cerevisiae. Biotechnology Journal 7. 594-601.
• Zhang J., Vaga  S., Chumnanpuen P., Kumar R., Vemuri G.N., Aebersold R., Nielsen J. (2011). Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae. Molecular systems biology 7 (1), 545.
• Chumnanpuen P., Kovitvadhi U., Chatchavalvanich K., Thongpan A., Kovitvadhi S. (2011). Morphological development of glochidia in artificial media through early juvenile of freshwater pearl mussel, Hyriopsis (Hyriopsis) bialatus Simpson, 1900. Invertebrate Reproduction & Development 55 (1), 40-52.
• Canelas A.B., Harrison N., Fazio A., Zhang J., Pitkanen, J.P., van den Brink J., Bakker B.M., Bogner, L., Bouwman J., Castrillo J.I., Cankorur A., Chumnanpuen P., Daran-Lapujade P., Dikicioglu D., van Eunen K., Ewald J.C., Heijnen J.J., Kirdar B., Mattila I., Mensonides F.I., Niebel A., Penttila M., Pronk J.T., Reuss M., Salusjarvi L., Sauer U., Sherman D., Siemann-Herzberg M., Westerhoff H., de Winde J., Petranovic D., Oliver S.G., Workman C.T., Zamboni N., Nielsen J. (2010). Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains. Nature Communication. 1, 145.